EVALUATE THE EFFICACY OF FERULA ASAFOETIDA RESIN ON PAIN OF KARPPA VAYU (PRIMARY DYSMENORRHEA)

Abstract

Dysmenorrhea is one of the most common clinical problems observed in regular practice and it is
a medical condition of pain during menstruation that interferes with daily activities.
Dysmenorrhea can be correlated with Karppa vayu in Siddha Medicine. An attempt has been
made to treat the dysmenorrhea with Siddha system of medicine.
A single blind comparative clinical study was conducted to evaluate the efficacy of Ferula
asafoetida resin powder on Karppa vayu (Primary dysmenorrhea) in comparison with standard
drug (mefenamic acid).
Forty patients with Karppa vayu disease were selected systematically. The Selected patients
were divided into 4 groups of 10 each. The groups A and B were treated with Ferula asafetida
resin powder, orally, thrice a day 650mg and 500mg respectively with the onset of pain, for 3
continuous menstrual cycles. The group C and D were treated by standard drug of 500mg of
mefenamic acid, orally, thrice a day from onset of pain for 3 continuous menstrual cycles.
Encouraging results were observed with the trial drug and when comparing Ferula asafetida
resin powder and mefenamic acid for severe pain, the 650mg of Ferula asafetida resin power
and 500mg of mefenamic acid both are statistically significant relief the pain because the P
values <0.005. The P-value of 650mg of Ferula asafetida resin powder and 500mg of mefenamic
acid was 0.000 and 0.001, respectively.
When comparing Ferula asafetida resin powder and mefenamic acid for moderate pain, the
500mg of Ferula asafetida resin powder and 500mg of mefenamic acid both are statistically
significant relief the pain because of the P-value <0.005. The p-value of both groups is 0.000.
In the present study, Ferula asafetida resin powder can be used as a highly effective internal
administrative medicine for Karppa vayu.