PRELIMINARY PHYTOCHEMICAL SCREENING, ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF SUDANESE DICHROSTACHYS CINEREA (L.) LEAVES

Abstract

The aim of this study is to investigate the chemical constituents of the methanolic extract of
Dichrostachys cinerea (L.) (Mimosaceae) leaves and to evaluate its potential antimicrobial and
antioxidant activity. Phytochemical analysis of the extract revealed the presence of (flavonoids
and saponins) in high concentration, (alkaloids, tannins, triterpenes, steroids and glycosides) in
moderate concentration and the absence of (coumarins and anthraquinones). The evaluation of
antimicrobial potential against Escherichia coli, Pseudomonasa aruginosa, Staphylococcus
aureus, Bacillus subtilis bacteria and the fungus Candida albicans showed (high, moderate, low)
activity. An Antioxidant activity was evaluated by measuring the capacity of the extract against
the stable DPPH radical. The study shows that this plant has therapeutic potential due to its high
radical scavenging activity.